| Prefecture |
Organization |
Institute Director |
Introduction of your Technology, Product and Study |
Technology Classification/Product Classification |
Contact |
| University |
Kobe University
|
Graduate School of Agricultural Science, Division of Agrobioscience, Laboratory of Glyco-chain Biochemistry
Masashi Mizuno, Ph.D.
|
(1) Searching for stimulating factors of immunological response cells within mushrooms and determining its molecular structure.(2) Effects of storage conditions on the anti-tumor polysaccharide content of edible mushrooms.(3) Constructing a system using small-intestinal epithelial cells for searching immunity stimulating factors and defining its mechanism of action.(4) Search for allergy suppressing factors and defining its mechanism of action.(5) Construction of an inflamatory intestinal disease model and searching for suppressing factors. |
[Technology Classification]
-A007/Basic Technology/Basic & Fundamental Technology/Cellular Network
-BA05/Life Innovation/Drug Discovery & Diagnosis/Drugs (Carbohydrate)
|
+81-78-803-5835
mizuno@kobe-u.ac.jp |
| University |
Kwansei Gakuin University
|
School of Science and Technology, Department of Bioscience
Susumu Imaoka
|
Organisms and cells live responding to various outside stimuli. Our laboratory has conducted research on 3 kinds of response-mechanisms. The first one is the response to hypoxia, the second one is immune response, especially in terms of its disorder (e.g. pollen allergy) and the third one is the response to the environmental hormones (endocrine-disturbing chemical substances
e.g. dioxin ). The first theme relates to fields ranging widely from cancers, cardiac infarction, and cerebral infarction to biogenesis. The tumor cells perceive hypoxia and cause angiogenesis in response for further proliferation. In differentiation during the process of genesis, responses to hypoxia are involved in cardiovascular and nervous formation. As for pollen allergy in the second theme, we have proceeded research, based on the presumption that the Ah receptor, as a receptor responding to foreign substances, is likely to be involved in the pathogenesis of pollen allergy in view of the fact that in areas where the air is more polluted by car emission etc., the pathogenesis rate is higher. With regard to the environmental hormones in the third theme, their influences on the developments of cranial nerves are under investigation. |
[Technology Classification]
-A007/Basic Technology/Basic & Fundamental Technology/Cellular Network
-CA03/Green Innovation/Environment & Energy/Bioremediation
-CC02/Green Innovation/Chemicals/Bio Refinery & Bio Process
|
+81-79-565-9052
ip.renkei@kwansei.ac.jp |
| University |
Kwansei Gakuin University
|
School of Science and Technology, Department of Bioscience
Katsunori Tanaka
|
Presently, we conduct research on two themes. One theme concerns the mechanism of cell function-regulation by SUMO which is one of the posttranslational protein modification factors. Proteins acquire diverse functions by undergoing various modifications after synthesis. SUMO is a modification molecule similar to ubiquitin and its biological function has attracted attention. We have been challenging to elucidate SUMO's biological function using yeasts and Arabidopsis as model organisms. The second theme is directed to the cell cycle checkpoints. Cells have checkpoint mechanisms such as percepting abnormalities such as DNA damage and reacting to the abnormalities by stopping their cell-cycle progression. Failure of this mechanism induces chromosome anomaly, which causes cancers in humans. We have been engaged in revealing the checkpoint mechanism, using yeasts as model organisms. |
[Technology Classification]
-A003/Basic Technology/Basic & Fundamental Technology/Analysis of Protein Function
-A007/Basic Technology/Basic & Fundamental Technology/Cellular Network
|
+81-79-565-9052
ip.renkei@kwansei.ac.jp |
| University |
Osaka University, Graduate School of Frontier Biosciences
|
Yanagida Lab
Toshio Yanagida
|
We are planning to construct a systems biology center where studies on molecular machinary, cells, imaging, modelling, and computation/theory and design are carried out to understand life processes. We also aim at developing brain sciences through combination of human brain function imaging, robotics, BMI, and information science in collaboration with NICT and ATR. |
[Technology Classification]
-A003/Basic Technology/Basic & Fundamental Technology/Analysis of Protein Function
-A007/Basic Technology/Basic & Fundamental Technology/Cellular Network
|
+81-6 6879 4632
softbio@fbs.osaka-u.ac.jp |
| Institute |
Osaka Bioscience Institute
|
Department of Molecular Behavioral Biology
Yoshihiro Urade
|
1)Chemotherapy of Duchenne Muscular dystrophy (DMD)We developed the specific inhibitor of hematopoietic PGD synthase based of the crystal structure. The HPGDS inhibitors ameliolate the progression of DMD.2)We invented a simple method for measuring quality of sleep without using special facilities or equipment which builds on our sleep-scoring system in animals based on analysis of the electroencephalogram (EEG) |
[Technology Classification]
-BA01/Life Innovation/Drug Discovery & Diagnosis/Drugs (Low Molecule)
-BA10/Life Innovation/Drug Discovery & Diagnosis/Diagnostic Equipment
-A007/Basic Technology/Basic & Fundamental Technology/Cellular Network
[Product Classification]
-BA02/Life Innovation/Drug Discovery & Diagnosis/Therapeutic Agent
-CB01/Green Innovation/Agriculture & Food/Food
|
+81-6-6872-4851
http://www.obi.or.jp/dept2/ |
