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Bio and Medical Device-related Sites of the Kansai Region

Sites Run by Local Governments The Industrial Technology Centers The Agricultural Experiment Stations and Related Facilities
Technical Colleges Public Research Institutes University Research Institutes
Industry Aid Agencies Other Supportive Organizations Industrial Organizations

Bio and Medical Device-related Sites Run by Local Governments
Local Government Name of Site Characteristics
Kobe City Kobe Biomedical Innovation Cluster At present 11 core research facilities, such as Institute of Biomedical Research and Innovation (IBRI), Riken Center for Developmental Biology (CDB), Riken Molecular Imaging R&D Center, are operating in the Kobe Life Science Cluster and a few more facilities of importance are now being introduced, including Riken Next-generation Supercomputer and New Kobe City General Hospital. These world top-class research facilities and private companies gathering in the cluster one after another, now reaching more than 200 companies, are engaged in energetic interactions and collaborations in translational research in regeneration medicine, development of new scientific discovery for therapeutic agents, development of new medical instruments etc.
Osaka Prefecture Northern Osaka Bio Medical Cluster Based on the industry-academia-government comprehensive strategy plan "Osaka Bio Strategy", Osaka prefecture seeks for the expansion of the bio cluster centered on pharmaceutical products and medical devices. The Northern Osaka Bio Medical Cluster website introduces the various efforts made for the Osaka-centered development of bio-related industries.
Osaka Prefecture Monodzukuri Business Information-center Osaka The Monodzukuri Business Information-center Osaka is a support base for manufacturing in small and medium enterprises. It is run by the Osaka prefecture and other related organizations.
Companies are introduced in relation to the biotechnology and medical field.
Osaka City Healthcare Frontier Osaka City pursues the encouragement of healthcare and preventive care industries as a part of promotion of a pilot project for manufacturing. The Healthcare Frontier website introduces the activities of the research teams of the Osaka City University Faculty of Medicine in support of the anti-fatigue and healing business field.
Higashi Osaka City Tech Plaza HIGASHIOSAKA At the Tech Plaza HIGASHIOSAKA website, the technology information of an approximate of 1100 companies within Higashi Osaka, Japan's number one small and medium enterprise city, are compiled in a searchable database in order to promote the exchange of technological information.
Shiga Prefecture Shiga BIO-INDUSTRY PORTAL SITE At the Shiga BIO-INDUSTRY PORTAL SITE, bio-related companies within the Shiga prefecture, information on current research development, and various commercialization assistance systems run by organizations such as the prefecture for use by bio venture companies are introduced.
Himeji City Hyogo-Himeji Business Satellite The Himeji Industrial Advancement Center works on enriching various research facilities and building industrial complexes such as the Nishi-Haruma Techno polis where the large synchrotron radiation facility Spring-8 is located. The website "Hyogo-Himeji Business Satellite" introduces the major companies and research institutes of Himeji City and supports the industrial advancement of Himeji.


● The Industrial Technology Centers

At Industrial Technology Centers, development research and industrial-academic-government collaboration is promoted with a community-based approach in technical fields of biotechnology and processing technology, which are fundamental to Bio and Medical Devices.

Industrial Technology Center of Fukui Prefecture

Industrial Research Center of Shiga Prefecture

Kyoto Municipal Industrial Research Institute

Kyoto Prefectural Technology Center for Small and Medium Enterprises

Osaka Municipal Technical Research Institute

Technology Research Institute of Osaka Prefecture

Hyogo Prefectural Institute of Technology

Nara Prefectural Institute of Industrial Technology

Industrial Technology Center of Wakayama Prefecture


The Agricultural Experiment Stations and Related Facilities of Each Prefecture

The Agricultural Experiment Stations of each prefecture support the research and development of green innovation. In recent years, the stations have gained the role of an agriculture, forestry, and fisheries technology center that integrates the fields to support biotechnology related projects.

Fukui Prefecture: Agricultural Experiment Station

Shiga Prefecture: Agricultural Technology Promotion Center

Kyoto Prefecture: Kyoto Prefectural Agriculture, Forestry, and Fisheries Technology Center

Osaka Prefecture: Research Institute of Environment, Agriculture, and Fisheries

Hyogo Prefecture: Technology Center for Agriculture, Forestry, and Fisheries

Nara Prefecture: Agricultural Experiment Station

Wakayama Prefecture: Wakayama Research Center of Agriculture, Forestry, and Fisheries


Technical Colleges in the Kansai Region

Technical colleges are higher education institutions with a 5 year unified education program for students who have graduated junior high school. There are 7 national and public technical colleges in the Kansai region.

In technical colleges, professional education centered on experiments and practical training is provided. In adjunct technical centers, research and technology education exceeds the limits of professional education and is promoted in an academic perspective based on current industrial trends and demands.

Advanced Research Center for Regional Cooperation, Fukui National College of Technology

Regional Collaboration Center of Technology , Maizuru National College of Technology

Osaka Prefectural College of Technology, Techno Center

Center of Technology, Akashi National College of Technology

Kobe City College of Technology, Regional Collaboration Research Center

Nara National College of Technology

Regional Collaboration Center of Technology, Wakayama National College of Technology


Public Research Institutes
Research Institute Characteristics  
National Institute of Advance Industrial Science and Technology (AIST) Kansai

In collaboration with industries and universities, AIST Kansai promotes research development centered on (1) energy technology and material technology aimed at the development of leading edge battery technology, (2) medical technology and health management technology for supporting a healthy and assuring life, and (3) information technology and standard technology to support industrial infrastructure. The Health Technology Research Institute was established in 2010 for research in the biomedical devices field.

National Institute of Advance Industrial Science and Technology (AIST) Kansai
National Institute of Biomedical Innovation Established in 2005 by the National Institute of Health Sciences、the National Institute of Biomedical Innovation contributes to development of common technology for pharmaceutical products, provides biological resources for research, and conducts research development. In the second term plan, the names of departments were changed to the (1) Department of Fundamental Technical Research, (2) Department of Disease Bioresources Research, and the (3) Department of Research and Development Promotion. The institute supports the research development of new pharmaceutical products and medical devices by private companies and universities. Research development of basic technology is conducted with emphasis on (1) Next-generation vaccines, (2) Development of a drug toxicity testing system, and (3) Treatment of the rare diseases. National Institute of Biomedical Innovation
National Cerebral and Cardiovascular Center, Independent Administrative Agency The National Cerebral and Cardiovascular Center makes full use of the world's most advanced human resources and devices in cooperation with the adjacent hospital to propel research development on the mechanism, diagnosis, treatment, and prevention of cardiovascular diseases. To provide top level medicinal care, the hospital, research institute, research development center, and administrative department unite in order to promote comprehensive countermeasures against cardiovascular diseases (i.e. heart disease in adults and children, vascular disease, cerebral vascular disease). Together as a whole, the center develops preventions, diagnosis, and treatments for cardiovascular diseases, elucidates the cause and pathological condition of cardiovascular diseases, and trains professional technologists. National Cerebral and Cardiovascular Center, Independent Administrative Agency
Institute of Biomedical Research and Innovation laboratory(IBRI) IBRI is a core institution designed to promote translationalresearch bridging basic research and clinical applicationin three target fields-R&D of medical devices, support forclinical research and trials,and clinical applicationof regenerative medicine.The institute has a hospital function with 60 beds, andprovides advanced therapies in the areas of imagingmedicine, clinical research and regenerative medicine totackle disorders that cannot be treated with standard medicine. Institute of Biomedical Research and Innovation laboratory
Translational Research Informatics Center(TRI) TRI was founded by the Ministry of Education, Culture, Sports,Science and Technology (MEXT) and Kobe City as the first data center / analysis center in Japanese academia. TRI provide clinical study/trial consultations to all clinical researchers and comprehensive support from drawing up protocol to statistical analysis and paper writing of clinical studies/trials. Translational Research Informatics Center
RIKEN Center for Developmental Biology, Independent administrative agency RIKEN Center for Developmental Biology promotes research of basic developmental biology as well as research concerning stem cells and regenerative medicine aimed at the field of medicine. Through the close interaction of these different areas, the center is striving to contribute to the life science of the 21st century. A renowned research institute in the area of developmental biology, researchers at the institute unravel developmental and regenerative systems to gain an integrated understanding of life and conduct basic as well as animal model research to promote regenerative medicine in the form of cell therapy and tissue regeneration. RIKEN Center for Developmental Biology, Independent administrative agency
RIKEN Center for Molecular Imaging Science, Independent administrative agency The Molecular Imaging Research Program (MIRP) was reorganized and inaugurated as the Center for Molecular Imaging Science (CMIS) in October 2008 to further advance research, and is currently comprised of six teams and three units. During the first phase of the MIPR, we not only worked to develop fundamental technologies, but also contributed to innovations in drug discovery, diagnostics, and therapeutic biomarkers. Furthermore, from April 2010, the "Strategic Research Program for Molecular Imaging" ill be initiated by MEXT to link the research achievements made thus far to clinical applications and experimental research. CMIS is expected to play a leading role as a core center in this initiative. RIKEN Center for Molecular Imaging Science, Independent administrative agency
Spring-8 Large synchrotron radiation facility SPring-8 is a large synchrotron radiation facility which delivers the most powerful synchrotron radiation currently available. Consisting of narrow, powerful beams of electromagnetic radiation, synchrotron radiation is produced when electron beams, accelerated to nearly the speed of light, are forced to travel in a curved path by a magnetic field. The research conducted at SPring-8, located in Harima Science Park City, Hyogo Prefecture, Japan, includes nanotechnology, biotechnology and industrial applications. Spring-8 Large synchrotron radiation facility
RIKEN Next-Generation Supercomputer R&D Center The national project for developing the next-generation supercomputer is underway and expected to be completed by the year 2012. When operation begins, the supercomputer will be utilized by a wide variety of fields as a shared facility open to those from inside and outside of the country. The Kobe Biomedical Innovation Cluster is expected to utilize the facility in the life science field towards achieving leading edge medical technology and developing novel drugs with no side effects. RIKEN Next-Generation Supercomputer R&D Center
Provided by RIKEN
Osaka Bioscience Institute The opening of the Institute in October 1987 was conducted as one of the activities commemorating the 100th anniversary of the Osaka City organization. Through outstanding research related to bioscience and the fostering of exceptional research personnel, OBI is stimulating the development of bioscience and promoting projects that contribute to the development of scientific technologies. The research at OBI places great emphasis on the elucidation and resolution of new issues in the field of fundamental biological technologies, an area rich in originality. These efforts have led OBI to realize a number of unique, world-class research achievements and one of the key centers of lifre science research activity in the Kansai area. Osaka Bioscience Institute


University Research Institutes

Research institutes attached to national universities in the Kansai region conduct research development on frontier Bio and Medical Devices.

University Research Institute Characteristics
Osaka University Research Institute for Microbial Diseases, Osaka University The Research Institute for Microbial Diseases promotes the basic research of infectious diseases and research how to repress infectious diseases. The institute contributes to the discovery of new bacterial and viral pathogens, elucidation of pathogenesis, and the development of vaccines and diagnostic reagents. Research on isolation of causal genes for cancer and untreatable genetic diseases and analysis of its function is also conducted. There are 3 research divisions (Division of Infectious Diseases, Division of Host Defense, Division of Cellular and Molecular Biology) and centers such as the Intractable Infection Control Research Center and Genetic Information Experiment Center are fulfilling. The "Research Collaboration Center on Emerging and Re-emerging Infections" has been established within the Thailand National Institute of Health to repress emerging and re-emerging infections.
Institute for Protein Research, Osaka University Making full use of methods to analyze the higher order structure of protein molecules and supramolecular compounds, research on the regulation of gene expression, signal transduction in and out of the cell, and elucidation of the energy conversion mechanism of the body are carried out. The center also aims to elucidate how living organisms are created from a map of genomic codes by researching proteins. The center acts as a shared research facility and provides a base for collaborative research and interaction between researchers in the country. In an international perspective, the center is one of the 3 centers of the World Wide Protein Data Bank (wwPDB) and is responsible for the Asian and Oceania region. The center also acts as an international biological systems NMR databank (BMRM) center.
Center for Advanced Science and Innovation, Osaka University Under the slogan "Live Locally Grow Globally", Osaka University supports the collaboration of academia and the industry and constructs project in an effort to create university-launched innovation. Through utilization of open laboratory facilities and running a flexible organization, the center promotes activities that help create industries, such as collaborative research with industries, government-funded research, and founding university-launched ventures. The center's Incubation Division of Advanced Science and Technology includes the Department of Social and Environmental Medicine, Department of Functional Materials, and Department of Electronic Material and Systems Engineering. As of today (2011), collaborative research with the industry includes regenerative drug discovery, skin regeneration technology, and neuromodulation and neurosurgery.
Immunology Frontier Research Center, Osaka University Immunology is one of the fields in which Japan has acted as a leader.  At the Immunology Frontier Research Center, integrated research of "immunology", "imaging technology", and "bioinformatics" is carried out in order to further promote research.  Through integrated research, the center aims to develop the technology to visualize the dynamics, activity, and interactions of immunological cells in the body and to comprehensively understand the immune system.  More than 20 of world top level senior researchers invited from in and outside of the country conduct research in collaboration with domestic and international institutes in order to develop vaccines for infectious diseases using a new strategies and immunotherapy for infectious diseases and cancer.
Medical Center for Translational Research The Medical Center for Translational Research was established within the Osaka University Hospital in a mission to practice translational research for the future of medicine and convert them into commonly used treatments. The center researches in the fields of gene therapy, cell therapy, tissue engineering, treatment using robots, and innovative diagnostic imaging and therapy. A board consisting of inside and outside members judge and evaluate the clinical projects from protocol development to the evaluation of practice. In an effort to develop new medicine into common medicine, the center has placed an academia-industrial laboratory and conducts collaborative research, exchanges information with industries, and cultivates human resources.
Kyoto University Center for iPS Cell Research and Application, Kyoto University Established in 2010 as the world's first iPS research center, CiRA conducts basic research, preclinical research, and clinical application research of iPS cells.  CiRA's two primary missions are 1) to apply iPS cell technology to clinical treatment for patients suffering from diseases with no current treatment or from critical damages and 2) to function as the world's top level iPS cell research center and contribute to stem cell research and regenerative medicine.  The new research building of CiRA is equipped with core facilities for animal research and cell processing, and will serve as home to a full spectrum of translation research, making it possible to move seamlessly from basic scientific laboratories to preclinical and clinical teams.  CiRA is in cooperative relations with other departments of Kyoto University as well as with other domestic or international universities and research facilities.
Institute for Integrated Cell-Material Sciences, Kyoto University The Institute for Integrated Cell-Material Sciences merges materials science and cell biology and carries out integrated research holding the keywords "meso-control" and "stem cells". "Meso-control" is the dynamic system which works in the space between nano and bulk scale.  For example in cells, several dozen biomacromolecules coexist with membrane structures and receives the fluctuation of molecular movement and the outer environment, but also manages to carry out complex reactions such as signal transduction.  In order to research these meso-control systems of the cell, the Institute for Integrated Cell-Material Sciences aims at research development in the following three areas; 1) Meso-controlled environment friendly chemistry, 2) detoxification within the body and drug synthesis, 3) regenerative medicine by the smart material control of stem cells.

Research Institute for Sustainable Humanosphere (RISH)

In 2004, the Research Institute for Sustainable Humanosphere was established by combining the Wood Research Institute (WRI) and the Radio Science Center for Space and Atmosphere (RASC) of Kyoto University.  Defining the regions vital to human existence as "humanosphere", the primary objective of RISH is to assess and evaluate the current and future conditions of the humanosphere as well as to provide solutions to the problems which the humanosphere faces.  For example, the RISH researches the dynamics of the atmosphere by using high performance lasers in order to monitor the Earth's condition and conducts comprehensive research on usage of biomass and carbon dioxide fixation by trees in order to create a sustainable society.  Research development on a space power station that converts outer space solar energy into electricity and sends microwaves to the Earth is also underway.
Frontier Drug Discovery Research Center, Kyoto University In the Funding Program for World-Leading Innovative R&D on Science and Technology (FIRST), the "Development of the next generation mass spectrometry system and contribution toward drug discovery and diagnostics" project was accepted and launched in 2010.  In this project, Shimadzu Corporation will make development the world-leading high performance mass spectrometry system and Kyoto University will establish the Frontier Drug Discovery Research Center within the Graduate School of Pharmacology and conduct research on cancer and Alzheimer's disease using the mass spectrometry system.  The objectives are to discover biomarkers and create molecular targeted drugs for cancer (breast cancer and esophageal cancer) and to develop biomarkers and early diagnosis methods for Alzheimer's disease.
Institute for Virus Research, Kyoto University Since it was established in 1956 for research on prevention and treatment of viral diseases, the Institute for Virus Research has identified the pathogenic virus for human adult T cell leukemia, promoted cellular and molecular biological research of the host, and has elucidated the mystery of virus replication. Virus research is fusional and therefore at the institute, research is carried out by graduate students with various backgrounds in cooperating courses with the Graduate School of Medicine, Graduate School of Biostudies, Graduate School of Science, Graduate School of Pharmaceutical Sciences, and the Graduate School of Human and Environmental Studies. In 2010, the institute was approved as the research center of virus and life science in the 21st Centery COE program and became the "COE Formation in Frontier Life Sciences by Unifying Interactions".
Institute for Frontier Medical Sciences, Kyoto University Since its establishment in 1998, the Institute for Frontier Medical Sciences has continued to research actively in the fields of stem cell research, biological basics of regenerative medicine, and medical engineering. Constituted of 4 research divisions (biological function, tissue engineering, regeneration control and clinical application) and several adjunct facilities, the institute fulfills its important role in academic basic research of medicine and clinical application. The institute is also the only facility in Japan that establishes human ES cell lines and carries out a national bioresource enterprise that establishes and distributes ES cells to research facilities confirmed by the Minister of Education, Culture, Sports, Science, and Technology.
Institute for Chemical Research, Kyoto University The Institute for Chemical Research conducts pioneer and leading-edge research on chemistry in general and is expanding its fields into biology, physics, information science. There are 5 research divisions and 3 research centers. One of the laboratories of the Division of Biochemistry elucidates mechanisms of biological phenomena in the eyes of chemistry. At the Bioinformatics Center, novel informatics technology in the field of bioknowledge systems, biological information, and pathway engineering is developed with emphasis on databases, algorisms, and data mining and then applied to biological research
Clinical Research Center for Medical Equipment Development (CRCMeD), Kyoto University Hospital
The Clinical Research Center for Medical Equipment Development (CRCMeD)was established on April 1, 2011 as an organization of Kyoto UniversityHospital, with the aim of creating innovative medical equipment andapplying them in clinical use quickly as well as cultivating humanresource capable of medical device development. Our Center, as anindustry-academia-government collaboration center, promotes promisingresearch projects for next generation of medical equipment andtechnology, focusing on clinical research which is considered abottleneck on the development of medical equipment.
Kobe University Organization of Advanced Science and Technology, Kobe University The Organization of Advanced Science and Technology in Kobe University is a unique organization that encourages the interaction and promotes interdisciplinary research of 5 natural science graduate schools (Science, Engineering, System Informatics, Agriculture, and Maritime Sciences). The "22 Core Research Teams" and "Research Centers" constitute the organization. The "22 Core Research Teams" perform research in emerging or integrated fields and provide cross-sectional education by passing on the fruits of research to education in the 5 graduate schools. The "Research Centers" introduced below carry forward frontier research on each of their individual and characteristic themes.
[Organization of Advanced Science and Technology, Kobe University]
Biosignal Research Center
Established in 1990 in a mission to elucidate intracellular signal transduction mechanisms, the Biosignal Research Center joined the Organization of Advanced Science and Technology in 2007 and renewed its research activity. Current research projects include intracellular signal transduction of the nervous system, mechanisms of signals and cell functional control, and activation control mechanisms of protein kinases. In the "Target Support for Creating World-standard Research and Education Bases (Centers of Excellence)" by the Ministry of Education, Culture, Sports, Science and Technology, the center was the core facility for the 2002 Base for Life Science "Function of Proteins in Signal Transduction".
[Organization of Advanced Science and Technology, Kobe University]
Research Center for Environmental Genomics
This center aims at solving global environmental issues through the research of "Environmental Genes" (collective term for a great variety of genes related to the interaction between the environment and organisms), elucidating the function of these genes, and controlling the relationship between the environment and organisms. At the center, full-time staff carry out educational and research activity, students from other departments utilize the facility, academic lectures and training sessions are held, information concerning genetic modifying experiments is provided, and ordered analysis of the primary structure of DNA and proteins is conducted.
[Organization of Advanced Science and Technology, Kobe University]
Molecular Photoscience Research Center
Kobe University has made many distinguished achievements in the molecular photoscience field such as research on ultrahigh resolution spectrums. The Molecular Photoscience Research Center was established as a collaborative education and research facility within the university in 2001. Constituted of the Laser Molecular Photoscience Laboratory, Ultrafast Photoscience Laboratory, and Coherent Photoscience Laboratory, the center aims at becoming an international research base for promoting basic photoscience research. Currently, the three main themes of research are 1) Elucidation of molecular structures and photo-induced molecular processes, 2) Controlling molecules by photons and the control/conversion of photons by physical matters, and 3) Development of high efficiency lasers with ultimate performance and spectrometry/measurement technology.
[Organization of Advanced Science and Technology, Kobe University]
Kobe University Research Center For Inland Seas (KURCIS)
The Kobe University Research Center For Inland Seas is located on the eastern end of the Seto Inland Sea.  Through education, research, and investigation from the standpoint of preservation of marine environments and organisms, the center elucidates the origins and functional mechanisms of the inland sea (enclosed coastal seas) and discovers the diversity and dynamics of the marine life inhabiting the area.  The center is active in cooperative research with various organizations as well as industry-government-academia collaborative research and is striving to contribute to the society by providing acquired information and technology on themes such as "restoration of the coastal environment by creating sea grass beds" and "improving water quality by using algae".
Kobe University Center for Infectious Diseases The Kobe University Center for Infectious Diseases is constituted of a total of 11 groups including 8 basic research groups and 3 clinical research groups. The center functions as an educational and research base for integrated basic and clinical research of inflectional diseases by developing drugs, shaping the healthcare system, and cultivating human resources. In cooperation with the WHO Kobe Center, Hyogo Prefecture Institute of Public Health and Consumer Sciences, and the Public Health Research Institute of Kobe City, the center is the base for infection control in the Hyogo prefecture. International cooperation with Asian countries is also carried out for active development and improvement of the prevention, diagnosis, and treatment of emerging and reemerging infectious diseases (especially the H5N1 bird flu super flu, West Nile Fever, Japanese encephalitis, Virus hepatitis, Dengue Fever, etc.).
University of Fukui University of Fukui Biomedical Imaging Research Center The Biomedical Imaging Research Center was established in 1994 as part of the University of Fukui Medical Department to support the medical use of radiation. Using cyclotron and positron emission tomography(PET), the center aims to promote basic and clinical research for diagnosis and prevention of diseases by visualizing molecular signals which reflect functional changes caused by illness. Recent research has revealed that in aging and diseases such as cancer, several molecules are involved in the abnormalities at the genetic level. As the positron nuclear species are suited for labeling these molecules, basic research aiming to utilize these species for the imaging of functional abnormalities is currently underway.


Bio and Medical Device Industry Aid Agencies

In February 2010, the "Kansai Region Council of Health and Longevity Related Industry Stimulation" was inaugurated in order to promote the Broad-based Plan of the Act on the Promotion of Establishment of Enterprises. Through broad-based cooperation of the government and industry support organizations, frontier research centers and a wide range of industrial resources are exploited to carry out supporting projects for industrial-academic alliances and cultivation of human resources. The conference committee includes the local government and the following industrial support organizations.

Osaka Chamber of Commerce and Industry

The Kobe Chamber of Commerce and Industry

Senri Life Science Foundation

Foundation for Biomedical Research and Innovation

Kobe Industry Promotion Foundation

Advanced Scientific Technology & Management Research Institute of KYOTO

Association of Bio Business Creation

NPO Kinki Bio-Industry Development


Other Supportive Organizations

Shiga Prefecture Industrial Support Center


Industrial Organizations

Osaka Pharmaceutical Manufacturers Association

Osaka Medical Instruments Association


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